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The diagnoses clusters matrix page organizes all known diagnoses into groups. Each cluster is a grouping of several similar disorders.
The DxP provides with each cluster, informative text about the cluster's main features.
Most mental health disorders are on a spectrum with closely related disorders that have shared symptoms, genetic and environmental risk factors, and possibly shared neural substrates. A good example is the consolidation of autistic disorder, Asperger's disorder, and pervasive developmental disorder into the Autism Spectrum Disorder cluster. Symptoms within this cluster represent a single continuum of mild to severe impairments in the areas of social communication and restrictive repetitive behaviors/interests rather than being distinct disorders.
The clusters’ matrix is organized with developmental and lifespan considerations, and according to internalized and externalized disorders. It starts with diagnoses thought to reflect developmental processes that manifest early in childhood (e.g., neurodevelopmental and schizophrenia spectrum and other psychotic disorders), followed by diagnoses that are more commonly manifested in adolescence and young adulthood (e.g., bipolar, depressive, and anxiety disorders), and ends with diagnoses relevant to older adulthood (e.g., neurocognitive disorders).
This organizational structure facilitates the comprehensive use of lifespan information to assist in establishing a diagnosis. In addition, after the neurodevelopmental disorders, the clusters are organized according to the following criterion: internalized (emotional and somatic) disorders, externalized (impulse-control) disorders, neurocognitive disorders, and other disorders. "Internalized disorders" are characterized by depressed mood, anxiety, and somatic symptoms. "Externalized disorders" include disorders exhibiting antisocial behaviors, impulsive and disruptive conduct disturbances, addictions and substance use symptoms, and impulse-control disorders.
The cluster of 'Other Conditions of Clinical Importance' contain conditions that are not mental disorders but that may be encountered by mental health practitioners. These conditions may be listed as the reason for clinical visits in addition to, or in place of, the mental disorders listed in the other clusters. A separate sub-cluster is devoted to 'other conditions that may be a focus of clinical attention'. These include relational problems, issues related to abuse and neglect, problems with adherence to treatment regimens, obesity, antisocial behavior, and malingering. There is also a separate sub-cluster for medication-induced mental disorders and other adverse effects of medication that may be assessed and treated by clinicians in mental health practice.
The DxP provides an easy way to navigate between clusters and diagnoses through the breadcrumbs navigation menu. Additionally, for each cluster, the DxP provides a 'Learn more' toggle where you can find additional information for each cluster.
Neurodevelopmental Disorders
Intellectual Disabilities
Intellectual Disability (Intellectual Developmental Disorder)
Global Developmental Delay
Unspecified Intellectual Disability (Intellectual Developmental Disorder)
Communication Disorders
Language Disorder
Speech Sound Disorder
Childhood-Onset Fluency Disorder (Stuttering)
Social (Pragmatic) Communication Disorder
Unspecified Communication Disorder
Autism Spectrum Disorder
Autism Spectrum Disorder
Attention-Deficit/Hyperactivity Disorder
Attention-Deficit/Hyperactivity Disorder
Other Specified Attention-Deficit/Hyperactivity Disorder
Unspecified Attention-Deficit/Hyperactivity Disorder
Specific Learning Disorder
Specific Learning Disorder
Motor Disorders
Developmental Coordination Disorder
Stereotypic Movement Disorder
Tic Disorders
Tourette's Disorder
Persistent (chronic) Motor or Vocal Tic Disorder
Provisional Tic Disorder
Other Specified Tic Disorder
Unspecified Tic Disorder
Other Neurodevelopmental Disorders
Other Specified Neurodevelopmental Disorder
Unspecified Neurodevelopmental Disorder
Schizophrenia and Other Psychotic Disorders
Schizotypal (Personality) Disorder
Delusional Disorder
Brief Psychotic Disorder
Schizophreniform Disorder
Schizophrenia
Schizoaffective Disorder
Substance/Medication-Induced Psychotic Disorder
Psychotic Disorder Due to Another Medical Condition
Catatonia
Catatonia Associated With Another Mental Disorder (Catatonia Specifier)
Catatonic Disorder Due to Another Medical Condition
Unspecified Catatonia
Other Specified Schizophrenia Spectrum and Other Psychotic Disorder
Unspecified Schizophrenia Spectrum and Other Psychotic Disorder
Mood Disorders
Bipolar and Related Disorders
Bipolar I Disorder
Bipolar II Disorder
Cyclothymic Disorder
Substance/Medication-Induced Bipolar and Related Disorder
Bipolar and Related Disorder Due to Another Medical Condition
Other Specified Bipolar and Related Disorder
Unspecified Bipolar and Related Disorder
Depressive Disorders
Disruptive Mood Dysregulation Disorder
Major Depressive Disorder
Persistent Depressive Disorder (Dysthymia)
Premenstrual Dysphoric Disorder
Substance/Medication-Induced Depressive Disorder
Depressive Disorder Due to Another Medical Condition
Other Specified Depressive Disorder
Unspecified Depressive Disorder
Anxiety Disorders
Separation Anxiety Disorder
Selective Mutism
Specific Phobia
Social Anxiety Disorder (Social Phobia)
Panic Disorder
Panic Attack Specifier
Agoraphobia
Generalized Anxiety Disorder
Substance/Medication-Induced Anxiety Disorder
Anxiety Disorder Due to Another Medical Condition
Other Specified Anxiety Disorder
Unspecified Anxiety Disorder
Obsessive-Compulsive and Related Disorders
Obsessive-Compulsive Disorder
Body Dysmorphic Disorder
Hoarding Disorder
Trichotillomania (Hair-Pulling Disorder)
Excoriation (Skin-Picking) Disorder
Substance/Medication-Induced Obsessive-Compulsive and Related Disorder
Obsessive-Compulsive and Related Disorder Due to Another Medical Condition
Other Specified Obsessive-Compulsive and Related Disorder
Unspecified Obsessive-Compulsive and Related Disorder
Trauma- and Stress-Related Disorders
Reactive Attachment Disorder
Disinhibited Social Engagement Disorder
Posttraumatic Stress Disorder
Posttraumatic Stress Disorder for Children 6 Years and Younger
Acute Stress Disorder
Adjustment Disorders
Other Specified Trauma- and Stressor-Related Disorder
Unspecified Trauma- and Stressor-Related Disorder
Dissociative Disorders
Dissociative Identity Disorder
Dissociative Amnesia
Depersonalization/Derealization Disorder
Other Specified Dissociative Disorder
Unspecified Dissociative Disorder
Somatic Symptom and Related Disorders
Somatic Symptom Disorder
Illness Anxiety Disorder (hypochondriasis)
Conversion Disorder (Functional Neurological Symptom Disorder)
Psychological Factors Affecting Other Medical Conditions
Factitious Disorder
Factitious Disorder Imposed on Self
Factitious Disorder Imposed on Another
Other Specified Somatic Symptom and Related Disorder
Unspecified Somatic Symptom and Related Disorder
Feeding and Eating Disorders
Pica
Rumination Disorder
Avoidant/Restrictive Food Intake Disorder
Anorexia Nervosa
Bulimia Nervosa
Binge-Eating Disorder
Other Specified Feeding or Eating Disorder
Unspecified Feeding or Eating Disorder
Elimination Disorders
Enuresis
Encopresis
Other Specified Elimination Disorder
Unspecified Elimination Disorder
Sleep-Wake Disorders
Insomnia Disorder
Hypersomnolence Disorder
Narcolepsy
Breathing-Related Sleep Disorders
Obstructive Sleep Apnea Hypopnea
Central Sleep Apnea
Sleep-Related Hypoventilation
Circadian Rhythm Sleep-Wake Disorders
Parasomnias
Non-Rapid Eye Movement Sleep Arousal Disorders
Nightmare Disorder
Rapid Eye Movement Sleep Behavior Disorder
Restless Legs Syndrome
Other Specified Insomnia Disorder
Unspecified Insomnia Disorder
Other Specified Hypersomnolence Disorder
Unspecified Hypersomnolence Disorder
Substance/Medication-Induced Sleep Disorder
Other Specified Sleep-Wake Disorder
Unspecified Sleep-Wake Disorder
Sexual - Dysfunctions, Disorders and Gender Dysphoria
Sexual Dysfunctions
Delayed Ejaculation
Erectile Disorder
Female Orgasmic Disorder
Female Sexual Interest/Arousal Disorder
Genlto-Pelvic Pain/Penetration Disorder
Male Hypoactive Sexual Desire Disorder
Premature (Early) Ejaculation
Substance/Medication-Induced Sexual Dysfunction
Other Specified Sexual Dysfunction
Unspecified Sexual Dysfunction
Paraphilic Disorders
Voyeuristic Disorder
Exhibitionistic Disorder
Frotteuristic Disorder
Sexual Masochism Disorder
Sexual Sadism Disorder
Pedophilic Disorder
Fetishistic Disorder
Transvestic Disorder
Other Specified Paraphilic Disorder
Unspecified Paraphilic Disorder
Gender Dysphoria
Gender Dysphoria
Gender Dysphoria in Adolescents and Adults
Other Specified Gender Dysphoria
Unspecified Gender Dysphoria
Disruptive, Impulse-Control, and Conduct Disorders
Oppositional Defiant Disorder
Intermittent Explosive Disorder
Conduct Disorder
Antisocial Personality Disorder
Pyromania
Kleptomania
Other Specified Disruptive, Impulse-Control, and Conduct Disorder
Unspecified Disruptive, Impulse-Control, and Conduct Disorder
Substance-Related and Addictive Disorders
Alcohol-Related Disorders
Alcohol Use Disorder
Alcohol Intoxication
Alcohol Withdrawal
Other Alcohol-induced Disorders
Unspecified Alcohol-Related Disorder
Caffeine-Related Disorders
Caffeine Intoxication
Caffeine Withdrawal
Other Caffeine-Induced Disorders
Unspecified Caffeine-Related Disorder
Cannabis-Related Disorders
Cannabis Use Disorder
Cannabis Intoxication
Cannabis Withdrawal
Other Cannabis-Induced Disorders
Unspecified Cannabis-Induced Disorders
Hallucinogen-Related Disorders
Phencyclidine Use Disorder
Other Hallucinogen Use Disorder
Phencyclidine Intoxication
Other Hallucinogen Intoxication
Hallucinogen Persisting Perception Disorder
Other Phencyclidine-induced Disorders
Other Hallucinogen-induced Disorders
Unspecified Phencyclidine-Related Disorder
Unspecified Hallucinogen-Related Disorder
Inhalant-Related Disorders
Inhalant Use Disorder
Inhalant Intoxication
Other Inhalant-Induced Disorders
Unspecified Inhalant-Related Disorder
Opioid-Related Disorders
Opioid Use Disorder
Opioid Intoxication
Opioid Withdrawal
Other Opioid-Induced Disorders
Unspecified Opioid-Related Disorder
Sedative-, Hypnotic-, or Anxiolytic-Related Disorders
Sedative, Hypnotic, or Anxiolytic Use Disorder
Sedative, Hypnotic, or Anxiolytic Intoxication
Sedative, Hypnotic, or Anxiolytic Withdrawal
Other Sedative-, Hypnotic-, or Anxiolytic-Induced Disorders
Unspecified Sedative-, Hypnotic-, or Anxiolytic-Related Disorder
Stimulant-Related Disorders
Stimulant Use Disorder
Stimulant Intoxication
Stimulant Withdrawal
Other Stimulant-Induced Disorders
Unspecified Stimulant-Related Disorder
Tobacco-Related Disorders
Tobacco Use Disorder
Tobacco Withdrawal
Other Tobacco-Induced Disorders
Unspecified Tobacco-Related Disorder
Other (or Unknown) Substance-Related Disorders
Other (or Unknown) Substance Use Disorder
Other (or Unknown) Substance Intoxication
Other (or Unknown) Substance Withdrawal
Other (or Unknown) Substance-Induced Disorders
Unspecified Other (or Unknown) Substance-Related Disorder
Non-Substance-Related Disorders
Gambling Disorder
Neurocognitive Disorders
Delirium
Delirium
Other Specified Delirium
Unspecified Delirium
Major and Mild Neurocognitive Disorders
Major Neurocognitive Disorder
Major NCD Due to Alzheimer's Disease
Major Frontotemporal NCD
Major NCD With Lewy Bodies
Major Vascular NCD
Major NCD Due to Traumatic Brain Injury
Substance/Medication-Induced Major NCD
Major NCD Due to HIV Infection
Major NCD Due to Prion Disease
Major NCD Due to Parkinson's Disease
Major NCD Due to Huntington's Disease
Major NCD Due to Another Medical Condition
Major NCD Due to Multiple Etiologies
Mild Neurocognitive Disorder
Mild NCD Due to Alzheimer's Disease
Mild Frontotemporal NCD
Mild NCD With Lewy Bodies
Mild Vascular NCD
Mild NCD Due to Traumatic Brain Injury
Substance/Medication-Induced Mild NCD
Mild NCD Due to HIV Infection
Mild NCD Due to Prion Disease
Mild NCD Due to Parkinson's Disease
Mild NCD Due to Huntington's Disease
Mild NCD Due to Another Medical Condition
Mild NCD Due to Multiple Etiologies
Unspecified Neurocognitive Disorder
Personality Disorders
General Personality Disorder
Paranoid Personality Disorder
Schizoid Personality Disorder
Schizotypal Personality Disorder
Antisocial Personality Disorder
Borderline Personality Disorder
Histrionic Personality Disorder
Narcissistic Personality Disorder
Avoidant Personality Disorder
Dependent Personality Disorder
Obsessive-Compulsive Personality Disorder
Personality Change Due to Another Medical Condition
Other Specified Personality Disorder
Unspecified Personality Disorder
Other Mental Disorders
Other Specified Mental Disorder Due to Another Medical Condition
Unspecified Mental Disorder Due to Another Medical Condition
Other Specified Mental Disorder
Unspecified Mental Disorder
No Diagnosis or Condition
Other Conditions of Clinical Importance
Other Conditions That May Be a Focus of Clinical Attention
Relational Problems
Problems Related to Family Upbringing
Parent-Child Relational Problem
Sibling Relational Problem
Upbringing Away From Parents
Child Affected by Parental Relationship Distress
Abuse and Neglect
Child Maltreatment and Neglect Problems
Child Physical Abuse
Child Sexual Abuse
Child Neglect
Child Psychological Abuse
Adult Maltreatment and Neglect Problems
Spouse or Partner Violence, Physical
Spouse or Partner Violence, Sexual
Spouse or Partner Neglect
Spouse or Partner Abuse, Psychological
Adult Abuse by Non-spouse or Non-partner
Educational and Occupational Problems
Educational Problems
Academic or Educational Problem
Occupational Problems
Problem Related to Current Military Deployment Status
Other Problem Related to Employment
Housing and Economic Problems
Housing Problems
Homelessness
Inadequate Housing
Discord With Neighbor, Lodger, or Landlord
Problem Related to Living in a Residential Institution
Economic Problems
Lack of Adequate Food or Safe Drinking Water
Extreme Poverty
Low Income
Insufficient Social Insurance or Welfare Support
Unspecified Housing or Economic Problem
Other Problems Related to the Social Environment
Phase of Life Problem
Problem Related to Living Alone
Acculturation Difficulty
Social Exclusion or Rejection
Target of (Perceived) Adverse Discrimination or Persecution
Unspecified Problem Related to Social Environment
Problems Related to Crime or Interaction With the Legal System
Victim of Crime
Conviction in Civil or Criminal Proceedings Without Imprisonment
Imprisonment or Other Incarceration
Problems Related to Release From Prison
Problems Related to Other Legal Circumstances
Other Health Service Encounters for Counseling and Medical Advice
Sex Counseling
Other Counseling or Consultation
Problems Related to Other Psychosocial, Personal, and Environmental Circumstances
Religious or Spiritual Problem
Problems Related to Unwanted Pregnancy
Problems Related to Multiparity
Discord With Social Service Provider, Including Probation Officer, Case Manager, or Social Services Worker
Victim of Terrorism or Torture
Exposure to Disaster, War, or Other Hostilities
Other Problem Related to Psychosocial Circumstances
Unspecified Problem Related to Unspecified Psychosocial Circumstances
Other Circumstances of Personal History
Other Personal History of Psychological Trauma
Personal History of Self-Harm
Personal History of Military Deployment
Other Personal Risk Factors
Problem Related to Lifestyle
Adult Antisocial Behavior
Child or Adolescent Antisocial Behavior
Problems Related to Access to Medical and Other Health Care
Unavailability or Inaccessibility of Health Care Facilities
Unavailability or Inaccessibility of Other Helping Agencies
Nonadherence to Medical Treatment and Malingering
Nonadherence to Medical Treatment
Malingering
Overweight, Wandering, and Borderline Intelligent
Overweight or Obesity
Wandering Associated With a Mental Disorder
Borderline Intellectual Functioning
Movement Disorders and Other Adverse Effects of Medication
Parkinsonism
Neuroleptic-Induced Parkinsonism
Other Medication-Induced Parkinsonism
Neuroleptic Malignant Syndrome
Medication-Induced Acute Dystonia
Medication-Induced Acute Akathisia
Tardive Dyskinesia
Tardive Dystonia
Tardive Akathisia
Medication-Induced Postural Tremor
Other Medication-Induced Movement Disorder
Antidepressant Discontinuation Syndrome
Other Adverse Effect of Medication